Home Alzheimer’s Disease Trastuzumab Deruxtecan Shows Promise in HER2 Targeted Therapy

Trastuzumab Deruxtecan Shows Promise in HER2 Targeted Therapy

The antibody-drug conjugate trastuzumab deruxtecan (T-DXd) showed promising activity in multiple non-breast/non-gastric cancer types with heavily pretreated HER2-expressing or HER2-mutant solid tumors, according to a recent study published in Cancer Discovery.1

More specifically, the T-DXd combination showed even greater antitumor activity in patients with HER2-mutant non-small cell lung cancer (NSCLC).

“HER2-targeted therapies have proven successful for patients with breast and gastric cancers; however, there are no approved HER2-targeted therapies available for patients with other HER2-overexpressing or HER2-mutated malignancies,” Bob Li, MD, senior author on the study said in a press release. 2 “Conventional therapies for these other HER2-overexpressing cancers tend to have limited efficacy and considerable side effects. Additional treatment options are urgently needed for…

Continue Reading to the Source


Please enter your comment!
Please enter your name here

Most Popular

Reflections on Living With an Incurable Illness : braincancer

(I’ve checked with the moderators to make sure this is appropriate and a good fit for this subreddit. I'm a very private person, and...

This Foramen Magnum Meningioma almost killed me 18 years ago.

submitted by /u/dkrem Continue Reading to the Source

Patients, Family & Friends, and Healthcare professionals : braincancer

I am currently a PhD student based at the Marie Curie Palliative Care Research Centre at Cardiff University. My PhD is focussed on developing...

32 year old singer Tom Parker of The Wanted diagnosed with stage 4 glioblastoma

submitted by /u/Jexlan Continue Reading to the Source

Recent Comments