Home Alzheimer’s Disease Tepotinib in MET exon 14 Skipping NSCLC Induces Durable Responses

Tepotinib in MET exon 14 Skipping NSCLC Induces Durable Responses

Results from subgroup analyses of patients with MET exon 14 skipping non‒small cell lung cancer (NSCLC) from the single-arm, phase 2 study VISION study (NCT02864992) demonstrated durable clinical activity of tepotinib in both treatment-naïve and previously treated disease.1

In these data that were presented during the 2020 World Conference on Lung Cancer (WCLC) Singapore, 152 patients had 9 or more months of follow-up and were assessed for efficacy in Cohort A and 255 were evaluated for safety in Cohorts A and C as of data cut-off of July 1, 2020. Paul K. Paik, MD, clinical director of Thoracic Oncology Service at Memorial Sloan Kettering Cancer Center, presented the findings virtually at the meeting.

Patients with advanced, EGFR/ALK wild-type, METex14 skipping NSCLC received oral tepotinib 500 mg once daily. Efficacy outcomes were consistent in patients who received prior…

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