Patients with metastatic breast, pancreatic, lung, and colorectal cancer saw disease progression associated with deteriorating health-related quality of life, according to a recent study published in JAMA Network Open.
Global health-related quality of life was most associated with lung cancer (6.7 points [95% CI, 3.5-9.9 points]; P< .001) and pancreatic cancer (5.4 points [95% CI, 3.3-7.5 points]; P< .001). The association was least pronounced in colorectal cancer (3.5 points [95% CI, 1.3-5.7 points]; P= .002) and breast cancer (2.4 points [95% CI, 1.0-3.9 points]; P = .001).
“The objective of this analysis was to determine the association of disease progression with various health-related quality of life domains in patients with 1 of 4 frequent cancers in clinical routine practice,” wrote the researchers. “The findings suggest that disease progression is associated with a…