Home Alzheimer’s Disease Savolitinib Induces Encouraging Efficacy, Safety in MET-Driven Papillary Renal Cell Carcinoma

Savolitinib Induces Encouraging Efficacy, Safety in MET-Driven Papillary Renal Cell Carcinoma

Savolitinib showed encouraging efficacy data and an improved safety profile compared to the standard of care sunitinib (Sutent) in patients with MET-driven papillary renal cell carcinoma (RCC), according to study results presented at the 2020 ASCO Virtual Scientific Program.

The highly selective MET-tyrosine kinase inhibitor also yielded fewer grade 3 or 4 adverse events (AEs) while requiring fewer dose modifications than sunitinib, which performed more poorly than the external retrospective data anticipated.

“Although patient numbers and follow-up were limited, savolitinib demonstrated encouraging efficacy and an improved safety profile versus sunitinib,” said lead study author Toni K Choueiri, MD, director, Lank Center for Genitourinary Oncology and the Kidney Cancer Center, Dana-Farber Cancer Institute, in his presentation of the data.

Median progression-free survival (PFS)…

Continue Reading to the Source

LEAVE A REPLY

Please enter your comment!
Please enter your name here

Most Popular

Cause of Alzheimer’s disease traced to mutation in common enzyme

submitted by /u/scotsman81 Continue Reading to the Source

Reflections on Living With an Incurable Illness : braincancer

(I’ve checked with the moderators to make sure this is appropriate and a good fit for this subreddit. I'm a very private person, and...

This Foramen Magnum Meningioma almost killed me 18 years ago.

submitted by /u/dkrem Continue Reading to the Source

Recent Comments