Home Alzheimer’s Disease Researchers Develop Long Noncoding RNA-Based Immune Classes and Scores for Immunotherapy

Researchers Develop Long Noncoding RNA-Based Immune Classes and Scores for Immunotherapy

Immunotherapy is recommended for patients with bladder cancer that fall into the immune-active class, including 1 of the 4 distinct long noncoding RNA-based immune classes identified by trial researchers, according to a study published in JAMA Network Open.

The study also recommends that the long noncoding RNA score should be integrated into multiomic panels composed of tumor alteration burden, PD-L1 expression, cytotoxic T-lymphocyte (CTL) infiltration to act as a useful biomarker for precision immunotherapy.

“This study used signatures of (long noncoding RNAs) and CTL infiltration to identify 4 distinct immune classes in clinical cancer immunotherapy and recommends immunotherapy for patients in the immune-active class with both an immune-functional lncRNA signature and dense CTL infiltration,” wrote the researchers.

A total of 419 patients were analyzed, including 348 patients…

Continue Reading to the Source

LEAVE A REPLY

Please enter your comment!
Please enter your name here

Most Popular

Cause of Alzheimer’s disease traced to mutation in common enzyme

submitted by /u/scotsman81 Continue Reading to the Source

Reflections on Living With an Incurable Illness : braincancer

(I’ve checked with the moderators to make sure this is appropriate and a good fit for this subreddit. I'm a very private person, and...

This Foramen Magnum Meningioma almost killed me 18 years ago.

submitted by /u/dkrem Continue Reading to the Source

Patients, Family & Friends, and Healthcare professionals : braincancer

I am currently a PhD student based at the Marie Curie Palliative Care Research Centre at Cardiff University. My PhD is focussed on developing...

Recent Comments