Home Alzheimer’s Disease PSMA PET Imaging Agent 18F-DCFPyL Enables Better Detection of Localized Metastatic Lesions

PSMA PET Imaging Agent 18F-DCFPyL Enables Better Detection of Localized Metastatic Lesions

were detectable with a high correct localization rate (CLR) and a positive predictive value (PPV) when the investigational prostate-specific membrane antigen (PSMA) PET imaging agent 18F-DCFPyL, according to data from the pivotal phase 3 CONDOR study.

These results were reported at the 2021 Genitourinary Cancers Symposium as the FDA prepares to make a decision on a new drug application (NDA) for the prostate-specific membrane antigen (PSMA) PET imaging agent.1

The multicenter phase 3 CONDOR study (NCT03739684) enrolled men with rising prostate-specific antigen (PSA) after definitive therapy and negative or equivocal standard-of-care imaging. Patients were required to have a PSA level of 0.2 or higher if they had undergone radical prostatectomy (RP) or a PSA level of 2.0 or higher if they were treated with radiation therapy or cryotherapy.

The radiolabeled small molecule 18F-DCFPyL…

Continue Reading to the Source


Please enter your comment!
Please enter your name here

Most Popular

PHERGain II Trial Launched to Examine Chemotherapy-Free Treatment for Patients With HER2+ Breast Cancer

A clinical trial to support the use of a chemotherapy-free therapeutic approach has been launched and will aim to demonstrate that this approach is...

FDA Grants Breakthrough Therapy Designation to Tipifarnib for Treatment of HRAS-Mutant HNSCC

The FDA has granted breakthrough therapy designation to the investigational drug tipifarnib for the treatment of patients with recurrent or metastatic HRAS-mutant head and...

Treatment with PARP Inhibitors Increased Risk of Myelodysplastic Syndrome and Acute Myeloid Leukemia

Patients treated with PARP inhibitors saw an increased risk of myelodysplastic syndrome and acute myeloid leukemia (AML) versus patients treated with placebo, according to...

Salma Jabbour, MD, on Next Steps for the KEYNOTE-799 Study

The chief of Gastrointestinal Radiation Oncology at the Rutgers Cancer Institute of New Jersey discussed how she hopes the results of the KEYNOTE-799 study...

Recent Comments