Home Alzheimer’s Disease Possible Predictors of Treatment-Free Remission in Patients with CML

Possible Predictors of Treatment-Free Remission in Patients with CML

A study published in the British Journal of Haematology suggested that effective prediction of treatment-free remission (TFR) in patients with chronic myeloid leukemia (CML) may be successfully obtained with an effector-suppressor score, which is calculated using absolute natural killer (NK) cells, FoxP3+ regulatory T-cells (T-reg), and monocytic myeloid-derived suppressor cells (Mo-MDSCs).

According to corresponding author Yazad Irani, PhD, a post-doctoral researcher in the GVL and Immunotherapy group at SAHMRI, this work could save more patients with CML from the physical and financial costs related to treatment with tyrosine kinase inhibitors (TKIs).2

“With TKI treatment, many patients get to the stage where they have no detectable cancer in their blood,” Irani said in a press release. “About half of these patients can safely stop taking their medication, but it’s very…

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