Home Alzheimer’s Disease Phase III Study Shows Combination Treatment to be Effective for NSCLC

Phase III Study Shows Combination Treatment to be Effective for NSCLC

A phase III randomized clinical trial, published in JAMA Oncology, found that carboplatin-pemetrexed treatment followed by pemetrexed maintenance to be a valid option for first-line treatment of elderly patients with advanced nonsquamous non-small cell lung cancer (NSCLC).

The clinically significant benefit of the combination with regard to its effectiveness and tolerability suggests that it should be considered as a standard option for treatment in this setting, according to the researchers. 

“With the emerging role of pemetrexed in the treatment of nonsquamous NSCLC and the good tolerability of this drug, there was interest in evaluation of pemetrexed in combination with carboplatin for elderly patients with advanced nonsquamous NSCLC,” the authors wrote. “To the best of our knowledge, our study is the first phase III randomized clinical trial specifically designed for…

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