Home Alzheimer’s Disease Pembrolizumab Bests Docetaxel in 5-Year Survival in PD-L1+ Advanced NSCLC

Pembrolizumab Bests Docetaxel in 5-Year Survival in PD-L1+ Advanced NSCLC

After more than 5 years of follow-up for the phase 2/3 KEYNOTE-010 trial (NCT01905657), pembrolizumab (Keytruda) continues to outperform docetaxel as therapy for patients with previously treated, PD-L1–positive advanced non–small cell lung cancer (NSCLC) based on clinically meaningful differences in overall (OS) and progression-free survival (PFS).1

“We continue to see a clinically meaningful improvement in OS and PFS. Five-year rates more than doubled in the pembrolizumab-treated patients for overall survival, compared with those receiving docetaxel,” Roy S. Herbst, MD, PhD, ensign professor of medicine and professor of pharmacology, chief of medical oncology, Yale Cancer Center and Smilow Cancer Hospital, and associate cancer center director for translational research, Yale Cancer Center, said during a virtual presentation of the follow-up results that were presented at the…

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