Updated data regarding overall survival (OS) from the IMpower133 trial (NCT02763579) indicate that maintenance therapy with atezolizumab (Tecentriq) plus carboplatin and etoposide (CP/ET) is superior to placebo and CP/ET for the treatment of extensive-stage small cell lung cancer (ES-SCLC).1
Lead study author Martin Reck, MD, PhD, head of the Department of Thoracic Oncology at the Lung Clinic Grosshansdorf in Germany, presented OS and progression-free survival (PFS) results from the phase 3 trial at the 2020 World Conference on Lung Cancer Singapore.
Investigators found that median OS was longer in the atezolizumab + CP/ET (n = 154) compared with the placebo + CP/ET arm (n = 164) among patients in the maintenance population. The median duration of follow-up was 13.9 months at the April 24, 2018 data cutoff.
The median OS was 15.7 versus 11.3 months in favor of the experimental arm (HR,…