Local therapy provides durable tumor control for a majority of patients with desmoid tumors, but young patients, patients with an extremity location, and patients with large tumors are at increased risk of recurrence, according to a recent study published in Cancer.
The patient cohort underwent local therapy with surgery alone, radiation therapy (RT) alone, or combined modality therapy (RT and surgery). These results showed that systemic therapy should be considered as a front-line option for this increased risk of recurrence population when active treatment is indicated.
“(Desmoid tumors) are clinically unpredictable and can cause significant morbidity,” wrote the researchers. “Local therapy consisting of surgery, RT, or surgery and RT provides durable (local control) in a majority of patients. However, young patients, patients with large tumors, and patients with extremity…
