Home Alzheimer’s Disease FDA Approves Ripretinib Tablets for Advanced Gastrointestinal Stromal Tumor

FDA Approves Ripretinib Tablets for Advanced Gastrointestinal Stromal Tumor

The FDA approved ripretinib (Qinlock) tablets as the first new drug specifically approved as a fourth-line treatment for advanced gastrointestinal stromal tumor (GIST).

Ripretinib is now indicated for adult patients who have received prior treatment with 3 or more kinase inhibitor therapies, including imatinib (Gleevec).

“Despite the progress that has been made over the past 20 years in developing treatments for GIST, including 4 FDA-approved targeted therapies — imatinib in 2002, sunitinib (Sutent) in 2006, regorafenib (Stivarga) in 2013, and avapritinib (Ayvakit) earlier this year — some patients don’t respond to treatment and their tumors continues to progress,” Richard Padzur, MD, director of the FDA’s Oncology Center of Excellence and acting director of the Office of Oncologic Diseases in the FDA’s Center for Drug Evaluation and Research, said in a press…

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