Home Alzheimer’s Disease FDA Approves Pomalidomide for Patients with AIDS-Related Kaposi Sarcoma

FDA Approves Pomalidomide for Patients with AIDS-Related Kaposi Sarcoma

The FDA approved pomalidomide (Pomalyst) for patients with AIDS-related Kaposi sarcoma whose disease has become resistant to highly active antiretroviral therapy (HAART), or in patients with Kaposi sarcoma who are HIV-negative – the only oral agent for this patient population, and the first in more than 20 years.

“[Pomalidomide] has shown positive results in Kaposi sarcoma patients, regardless of their HIV status,” Robert Yarchoan, MD, chief of the HIV and AIDS Malignancy Branch within the Center for Cancer Research of the National Cancer Institute, said in a press release. “Also, it provides a therapy that is taken orally and works by a different mechanism of action than the cytotoxic chemotherapy drugs generally used to treat Kaposi sarcoma.”

Pomalidomide was granted accelerated approval, breakthrough therapy designation, and orphan drug designation based on overall…

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