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FDA Approves Luspatercept to Treat Anemia in Patients with Lower-Risk MDS

The FDA approved the first and only erythroid maturation agent, luspatercept-aamt (Reblozyl), to treat anemia in patients with lower-risk myelodysplastic syndromes (MDS), according to Bristol Meyers Squibb, the agent’s manufacturer.1

In particular, luspatercept is approved to treat anemia failing an erythropoiesis stimulating agent (ESA) and requiring 2 or more red blood cell (RBC) units over 8 weeks in adult patients with very low- to intermediate-risk MDS with ring sideroblasts (MDS-RS) or with MDS/myeloproliferative neoplasm with RS and thrombocytosis (MDS/MPN-RS-T). 

“(This) approval of Reblozyl is an important milestone for a majority of patients with myelodysplastic syndromes who have limited treatment options to address anemia associated with their disease. It also demonstrates our continued commitment to develop innovative products that improve the lives of patients…

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