Debu Tripathy, MD, breast medical oncologist at The University of Texas MD Anderson Cancer Center, spoke about the latest updates in the triple negative breast cancer space and the effect they could have for this patient population at the 37th Annual Miami Breast Cancer Conference.
Transcription:
Triple negative breast cancer is one of the more aggressive cancers and traditionally, we’ve been using chemotherapy really as our only drug. Other targets really haven’t revealed themselves as readily. PARP inhibition, as I mentioned earlier, is used in the triple negative cancers that are the subset of them that are related to BRCA 1 or 2 mutations. But in the early stage setting, really chemotherapy is still what we’re using. There are trials with neoadjuvant inhibitors of checkpoints, particularly with pembrolizumab (Keytruda), that are showing some promising early results with…