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Robert J. Motzer, MD, on Next Steps for the Phase 3 CLEAR Trial for Advanced RCC

Investigators compared lenvatinib plus either pembrolizumab or everolimus versus sunitinib in patients with advanced renal cell carcinoma in the CLEAR trial.According to results from...

Model Provides Template for High-Income & Emerging Economies to Plan Cancer Surgery Provision

A guideline-based model described in The Lancet Oncology may provide a new template for high-income and emerging economies to rationally plan and evaluate their...

Toni Choueiri, MD, on How New Data Impact the Standard of Care for RCC

Nivolumab (Opdivo) plus cabozantinib (Cabometyx) demonstrated improved efficacy and prolonged survival compared with sunitinib (Sutent) among patients with previously untreated advanced renal cell carcinoma...

Study Results Appear to Support Larotrectinib Use in NTRK+ Lung Cancer

Frequent and durable antitumor responses as well as extended survival were noted with the use of larotrectinib (Vitrakvi) in patients with NTRK gene fusion–positive...

Salma Jabbour, MD, on the Impact of the Ongoing KEYNOTE-799 Study

The chief of Gastrointestinal Radiation Oncology at the Rutgers Cancer Institute of New Jersey spoke about the possible implications of the KEYNOTE-799 study findings.Pembrolizumab...

Retrospective Analysis Using Social Vulnerability Index Highlights At Risk Populations Following Surgery

Following several common oncologic procedures, patients with a high Social Vulnerability Index (SVI) had a higher greater likelihood of having a complication, extended length...

Prioritizing AEs May Lead to Improvement in Communication Between Patients With CLL and Their Oncologists

Focusing the discussion on the risks of adverse events (AEs) with patient goals in mind has the potential to improve communication between oncologists and...

In B-Cell NHL, Off-the-Shelf NK Immunotherapy Shows Promise When Used With Chemotherapy and ASCT

Early results from a phase 2 trial (NCT03019640) showed that cord blood–derived natural killer (NK) immunotherapy plus high-dose chemotherapy and autologous stem cell transplant...

Adjuvant Sequential RT More Effective Than Concurrent RT or RT Alone for Patients with Cervical Cancer Following Hysterectomy

Sequential chemoradiation (SCRT) resulted in a higher disease-free survival (DFS) rate and lower risk of cancer death versus concurrent chemoradiation (CCRT) or radiation (RT)...

Timothy A. Yap, MBBS, PhD, FRCP, on COVID-19 Vaccination for Patients in Phase 1 Cancer Trials

The medical oncologist and physician scientist based at the University of Texas MD Anderson Cancer Center explained recommendations for SARS-CoV-2 vaccination in patients participating...

Black Women With Node-Negative Breast Cancer More Likely to Have High-Risk Recurrence Scores Than Non-Hispanic White Women

When comparing recurrence scores in the United States, investigators found that Black women were more likely to have a high-risk recurrence score and to...

Phase 1/2a Data Finds BI-1206 Antibody Restores Response to Rituximab in Patients With Relapsed Non-Hodgkin Lymphoma

BioInvent International AB recently announced interim data from a phase 1/2a trial of the antibody BI-1206 in combination with rituximab (Rituxan) to treat patients...

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Third COVID-19 Vaccine Earns Emergency Use Authorization Following Favorable Advisory Committee Meeting

The first single-dose COVID-19 vaccine was granted Emergency Use Authorization (EUA) by the FDA, according to its developer Janssen Pharmaceutical Companies of Johnson &...

Abiraterone Acetate, Apalutamide Likeliest to Improve Survival for Patients with Castration-Sensitive Prostate Cancer

In a comparison of systemic treatments as add-ons to androgen-deprivation therapy (ADT) for patients with metastatic castration-sensitive prostate cancer (mCSPC), abiraterone acetate (Zytiga) and...

Women of Minority Race/Ethnicity, Lower Socioeconomic Status Experience Lower Digital Breast Tomosynthesis Access

A cross-sectional study of digital breast tomosynthesis (DBT) screening published in JAMA Network Open indicated that women of minority race/ethnicity and lower socioeconomic status...

Michael Szarek, PhD, on the Outcomes of a Q-TWiST Analysis From the Phase 3 TIVO-3 Study

An analysis revealed that as a third- or fourth-line treatment for RCC, tivozanib significantly increased Q-TWiST compared with sorafenib, primarily through an increase in...