Home Alzheimer’s Disease Apalutimide Plus ADT Improves Survival in Nonmetastatic Castration-Resistant Prostate Cancer

Apalutimide Plus ADT Improves Survival in Nonmetastatic Castration-Resistant Prostate Cancer

Apalutimide (Erleada) plus androgen deprivation therapy (ADT) significantly improved overall survival (OS) when compared with ADT plus placebo in patients with nonmetastatic castration-resistant prostate cancer (nmCRPC), according to results from the phase III SPARTAN trial presented at the 2020 American Society of Clinical Oncology Virtual Scientific Program.1

Apalutimide previously received FDA approval for the treatment of nmCRPC in February of 2018 following an interim analysis that showed significant improvement in metastasis-free survival (MFS).

“This final analysis of SPARTAN demonstrated that apalutimide significantly improved survival in men with nonmetastatic castration-resistant prostate cancer,” said lead author and presenter Eric J. Small, MD of the University of California San Francisco Helen Diller Family Comprehensive Cancer Center. “And it did so despite a high…

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