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Adjuvant Sequential RT More Effective Than Concurrent RT or RT Alone for Patients with Cervical Cancer Following Hysterectomy

Sequential chemoradiation (SCRT) resulted in a higher disease-free survival (DFS) rate and lower risk of cancer death versus concurrent chemoradiation (CCRT) or radiation (RT) alone after surgery among women with early-stage cervical cancer, according to results from the randomized phase 3 STARS clinical trial (NCT00806117) which evaluated the 3 treatment modalities in a postoperative adjuvant treatment setting.

These study results, published in JAMA Oncology, support the use of SCRT as a preferred adjuvant treatment following radical hysterectomy for patients with early-stage cervical cancer.

“All of the findings together suggest that SCRT could be the most effective method among current adjuvant treatments for early-stage cervical cancer,” wrote the study authors, who were led by He Huang, MD.

In this multicenter, open-label trial, patients with FIGO (International Federation of…

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