Home Alzheimer’s Disease Adjuvant Osimertinib Does Not Adversely Affect Health-Related QOL for EGFR+ NSCLC

Adjuvant Osimertinib Does Not Adversely Affect Health-Related QOL for EGFR+ NSCLC

Patients receiving adjuvant osimertinib (Tagrisso) in the phase 3 ADAURA trial (NCT02511106) for EGFR-positive non–small cell lung cancer (NSCLC) experienced no clinically meaningful differences in health-related quality of life (HRQoL) measures versus placebo, according to an analysis on patient-reported outcomes (PROs) from the pivotal trial.1,2

Results indicated a high rate of compliance with regard to the completion of the Short Form-36 (SF-36) health survey, which remained at 85% or higher across all visits in both the osimertinib arm and the placebo arm. Physical component summary scores (PCS) and mental component summary scores (MCS) T-scores were also comparable between the arms (range, 46-47), and were only slightly below the mean values observed in the general population (0.3-0.4 SD below the normative mean).

Patients in both the osimertinib arm and the placebo arm…

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